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1 - 2 of 2 results found for ATXN7.

  1. The structural plasticity of SCA7 domains defines their differential nucleosome-binding...

    SAGA (Spt-Ada-Gcn5 acetyltransferase), a coactivator complex involved in chromatin remodelling, harbours both histone acetylation and deubiquitination activities. ATXN7/Sgf73 and ATXN7L3, two subunits of the SAGA deubiquitination module, contain an

  2. Modulation of the age at onset in spinocerebellar ataxia by CAG tracts in various genes.

    Polyglutamine-coding (CAG)n repeat expansions in seven different genes cause spinocerebellar ataxias. Although the size of the expansion is negatively correlated with age at onset, it accounts for only 50-70% of its variability. To find other

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