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1 - 10 of 151 results found for CDC42.

  1. New publication in Development for Pichaud Lab | LMCB - MRC...

    However, membrane localization of Baz, Par6-aPKC and Crb all depend on Cdc42. ... Altogether, we propose that Cdc42 drives morphogenesis by conferring apical identity, Par-complex assembly and apical accumulation of Crb.

    https://www.ucl.ac.uk/lmcb/news/sep/2019/new-publication-development-pichaud-lab

  2. New publication in Journal of Cell Science for Pichaud Lab | LMCB -...

    Abstract from the article:. Cdc42 – a member of the small Rho GTPase family – regulates cell polarity across organisms from yeast to humans. ... This complexity is mirrored by the fact that Cdc42 can exert its function through many effector proteins.

    https://www.ucl.ac.uk/lmcb/news/may/2019/new-publication-journal-cell-science-pichaud-lab

  3. Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic...

    http://iris.ucl.ac.uk/iris/publication/162269/1

  4. Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in...

    http://iris.ucl.ac.uk/iris/publication/162170/1

  5. Franck Pichaud | LMCB - MRC Laboratory for Molecular Cell Biology

    Cdc42 defines apical identity and regulates epithelial morphogenesis by promoting apical recruitment of Par6-aPKC and Crumbs. ... Regulation of Cdc42 and its effectors in epithelial morphogenesis.

    https://www.ucl.ac.uk/lmcb/users/franck-pichaud

  6. Review by Franck Pichaud in Frontiers in Cellular Neuroscience | LMCB...

    The conserved PAR complex, which in flies consists of Cdc42-PAR6-aPKC-Bazooka, and the transmembrane protein Crumbs (Crb) are key players during photoreceptor morphogenesis. ... Together Cdc42-PAR6-aPKC-Bazooka and Crb orchestrate the differentiation of

    https://www.ucl.ac.uk/lmcb/news/apr/2018/review-franck-pichaud-frontiers-cellular-neuroscience

  7. Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic...

    Rho GTPases play pivotal roles in regulating cell morphology. We previously showed that RhoA acts via ROKα to counteract the effects of the classical second messenger cyclic AMP on cell shape changes. Here we show that active Cdc42 also competes

    http://iris.ucl.ac.uk/iris/publication/281850/7

  8. Cdc42 & GSK-3: signals at the crossroads

    http://iris.ucl.ac.uk/iris/publication/8309/1

  9. New roles for Cdc42 and Rac in antigen uptake?

    http://iris.ucl.ac.uk/iris/publication/4094/1

  10. News | LMCB - MRC Laboratory for Molecular Cell Biology - UCL -...

    A new publication in Development for the Pichaud Lab  reveals that during development, the small RhoGTPase Cdc42 defines the side of epithelial cells that mediates nutrient (e.g.

    https://www.ucl.ac.uk/lmcb/news?page=5

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