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1 - 10 of 13 results found for EP300. Did you mean: p300

  1. Truncating mutations of the EP300 acetylase in human cancers

    http://iris.ucl.ac.uk/iris/publication/182358/3

  2. Mutations truncating the EP300 acetylase in human cancers

    http://iris.ucl.ac.uk/iris/publication/11300/1

  3. Mutations truncating the EP300 acetylase in human cancers

    The EP300 protein is a histone acetyltransferase that regulates transcription via chromatin remodelling and is important in the processes of cell proliferation and differentiation. EP300 acetylation of TP53 in response to DNA damage regulates its DNA

    http://iris.ucl.ac.uk/iris/publication/294595/7

  4. Genetic heterogeneity in Rubinstein-Taybi syndrome: delineation of the phenotype of the...

    BACKGROUND: Rubinstein-Taybi syndrome (RSTS) is a congenital disorder characterised by growth retardation, facial dysmorphisms, skeletal abnormalities and mental retardation. Broad thumbs and halluces are the hallmarks of the syndrome. RSTS is

    http://iris.ucl.ac.uk/iris/publication/89939/1

  5. Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300...

    CREB-binding protein and p300 function as transcriptional coactivators in the regulation of gene expression through various signal-transduction pathways. Both are potent histone acetyl transferases. A certain level of CREB-binding protein is

    http://iris.ucl.ac.uk/iris/publication/68983/1

  6. The miR-106b~25 cluster promotes bypass of doxorubicin-induced senescence and increase in...

    Resistance to chemotherapeutic treatment, which is indirectly responsible for many cancer deaths, is normally associated with an aggressive phenotype including increased cell motility and acquisition of invasive properties. Here we describe how

    http://iris.ucl.ac.uk/iris/publication/918974/2

  7. The miR-106b∼25 cluster promotes bypass of doxorubicin-induced senescence and increase in...

    Resistance to chemotherapeutic treatment, which is indirectly responsible for many cancer deaths, is normally associated with an aggressive phenotype including increased cell motility and acquisition of invasive properties. Here we describe how

    http://iris.ucl.ac.uk/iris/publication/931659/7

  8. Alzheimer's Disease Annotation | UCL Institute of Cardiovascular...

    Histone acetyltransferase p300. EP300. E1A binding protein p300. 15.

    https://www.ucl.ac.uk/cardiovascular/research/pre-clinical-and-fundamental-science
    /functional-gene-annotation/neurological-gene-0

  9. Two Adults With Rubinstein-Taybi Syndrome With Mild Mental Retardation, Glaucoma, Normal...

    The Rubinstein-Taybi syndrome (RTS; OMIM 180849) is a well-defined mental retardation/multiple congenital anomalies (MR/MCA) syndrome characterized by postnatal growth retardation, microcephaly, specific facial features, broad thumbs and halluces,

    http://iris.ucl.ac.uk/iris/publication/126257/1

  10. The transcriptional regulator ZNF398 mediates pluripotency and epithelial character...

    Human pluripotent stem cells (hPSCs) have the capacity to give rise to all differentiated cells of the adult. TGF-beta is used routinely for expansion of conventional hPSCs as flat epithelial colonies expressing the transcription factors POU5F1/OCT4,

    http://iris.ucl.ac.uk/iris/publication/1781747/1

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