1 - 6 of 6 results found for GAL3ST1.
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Emmanuelle Viré | MRC Prion Unit and Institute of Prion diseases -...
Emmanuelle Viré. e.vire@prion.ucl.ac.uk. Tel: 020 7679 5094. Courtauld Building, Room G01. • PubMed•. . . Research Synopsis. We explore if epigenetics is a hallmark of protein-based inheritance in neurodegeneration. Our research
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Programme 1 | MRC Prion Unit and Institute of Prion diseases - UCL –...
Recently we identified STX6 and GAL3ST1 as risk factors for CJD. ... At the UCL Institute of Prion Diseases (IoPD) we discovered that a common amino acid variant (V29M) of the sole enzyme involved in the synthesis of sulfatide (GAL3ST1 gene) confers a
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Genome-wide association study identifies risk variants for sporadic Creutzfeldt-Jakob...
Mammalian prions are lethal pathogens composed of fibrillar assemblies of misfolded prion protein. Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common being sporadic Creutzfeldt-Jakob disease (sCJD).
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Genetic risk factors for Creutzfeldt-Jakob disease
© 2020 Prion diseases are a group of fatal neurodegenerative disorders of mammals that share a central role for prion protein (PrP, gene PRNP) in their pathogenesis. Prions are infectious agents that account for the observed transmission of prion
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Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob...
BACKGROUND: Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common being sporadic Creutzfeldt-Jakob disease (sCJD). Variants in the PRNP gene that encodes prion protein are strong risk factors for sCJD
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