Advanced search
Search:  

1 - 10 of 18 results found for GCKR. Did you mean: gickr

  1. Associations between a Polymorphism in the Pleiotropic GCKR and Age-Related Phenotypes:...

    Background:The glucokinase regulatory protein encoded by GCKR plays an important role in glucose metabolism and a single nucleotide polymorphism (SNP) rs1260326 (P446L) in the gene has been associated with several age-related biomarkers, including

    http://iris.ucl.ac.uk/iris/publication/892597/7

  2. Gene-centric association signals for haemostasis and thrombosis traits identified with...

    Coagulation phenotypes show strong intercorrelations, affect cardiovascular disease risk and are influenced by genetic variants. The objective of this study was to search for novel genetic variants influencing the following coagulation phenotypes:

    http://iris.ucl.ac.uk/iris/publication/913334/2

  3. Genome-wide association study identifies loci influencing concentrations of liver enzymes...

    Concentrations of liver enzymes in plasma are widely used as indicators of liver disease. We carried out a genome-wide association study in 61,089 individuals, identifying 42 loci associated with concentrations of liver enzymes in plasma, of which

    http://iris.ucl.ac.uk/iris/publication/402422/1

  4. 2013 | Institute of Epidemiology & Health Care - UCL – University...

    Team. Journal of Nutrition, 143, 606-612, 2013 (PMID: 23468552). Associations between a polymorphism in the pleiotropic GCKR and Age-related phenotypes: the HALCyon programme.Alfred T, Ben-Shlomo Y, Cooper

    https://www.ucl.ac.uk/epidemiology-health-care/research/epidemiology-and-public-health/research
    /whitehall-ii/publications/2013

  5. Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma...

    OBJECTIVE: Fasting plasma glucose and risk of type 2 diabetes are higher among Indian Asians than among European and North American Caucasians. Few studies have investigated genetic factors influencing glucose metabolism among Indian Asians.

    http://iris.ucl.ac.uk/iris/publication/246786/2

  6. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related...

    OBJECTIVE: Whole-grain foods are touted for multiple health benefits, including enhancing insulin sensitivity and reducing type 2 diabetes risk. Recent genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms

    http://iris.ucl.ac.uk/iris/publication/430907/1

  7. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related...

    OBJECTIVE: Whole-grain foods are touted for multiple health benefits, including enhancing insulin sensitivity and reducing type 2 diabetes risk. Recent genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms

    http://iris.ucl.ac.uk/iris/publication/321800/2

  8. Genome-wide association analysis identifies variants associated with nonalcoholic fatty...

    Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA)

    http://iris.ucl.ac.uk/iris/publication/318474/1

  9. A gene-centric association scan for Coagulation Factor VII levels in European and African...

    Polymorphisms in several distinct genomic regions, including the F7 gene, were recently associated with factor VII (FVII) levels in European Americans (EAs). The genetic determinants of FVII in African Americans (AAs) are unknown. We used a 50,000

    http://iris.ucl.ac.uk/iris/publication/318764/2

  10. Bayesian Test for Colocalisation Between Pairs of Genetic Association Studies Using...

    Genetic association studies, in particular the genome-wide association study design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases and traits. The next challenge consists of understanding the molecular

    http://iris.ucl.ac.uk/iris/publication/872191/5

  11. Page: 1 2