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1 - 6 of 6 results found for HDAC3. Did you mean: hdac

  1. Genetic Knock-Down of Hdac3 Does Not Modify Disease-Related Phenotypes in a Mouse Model...

    http://iris.ucl.ac.uk/iris/publication/1129075/3

  2. Alison Lloyd | LMCB - MRC Laboratory for Molecular Cell Biology

    Development 145, dev170316. Rosenberg NH, et al (2018).  HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State.

    https://www.ucl.ac.uk/lmcb/users/alison-lloyd

  3. HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State

    © 2018 The Author(s) The formation of myelinating Schwann cells (mSCs) involves the remarkable biogenic process, which rapidly generates the myelin sheath. Once formed, the mSC transitions to a stable homeostatic state, with loss of this stability

    http://iris.ucl.ac.uk/iris/publication/1607277/1

  4. Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by...

    RATIONALE: Nkx2.5 is one of the most widely studied cardiac-specific transcription factors, conserved from flies to man, with multiple essential roles in both the developing and adult heart. Specific dominant mutations in NKX2.5 have been identified

    http://iris.ucl.ac.uk/iris/publication/411751/2

  5. Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor

    © 2019 Elsevier Masson SAS Herein, we report the discovery of a dual histone deacetylase inhibitor displaying a unique HDAC3/6 selectivity profile. An initial strategy to merge two epigenetic pharmacophores resulted in the discovery of potent HDAC6

    http://iris.ucl.ac.uk/iris/publication/1711208/1

  6. Histone deacetylase inhibitors containing chiral heterocyclic capping groups

    Histone deacetylase (HDAC) enzymes are one of the best characterised epigenetic targets; aberrant activity of one or more of the 11 zinc-dependent HDAC isoforms has been associated with many different cancers, as well as several other diseases. Some

    http://iris.ucl.ac.uk/iris/publication/1127594/1

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