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  1. Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to...

    Many individuals with multiple or large colorectal adenomas or early-onset colorectal cancer (CRC) have no detectable germline mutations in the known cancer predisposition genes. Using whole-genome sequencing, supplemented by linkage and association

    http://iris.ucl.ac.uk/iris/publication/840512/2

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