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1 - 5 of 5 results found for PSMC1. Did you mean: pasmcs

  1. TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory...

    http://iris.ucl.ac.uk/iris/publication/1113615/3

  2. Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and...

    Ubiquitin-positive intraneuronal inclusions are a consistent feature of the major human neurodegenerative diseases, suggesting that dysfunction of the ubiquitin proteasome system is central to disease etiology. Research using inhibitors of the 20S

    http://iris.ucl.ac.uk/iris/publication/152162/2

  3. The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen...

    In the past twenty years, evidence has accumulated to show that ubiquitinated proteins are a consistent feature of the intraneuronal protein aggregates (inclusions) that characterize chronic neurodegenerative disease. These findings may indicate

    http://iris.ucl.ac.uk/iris/publication/344698/2

  4. Identification of Interacting Protein Partners of TOPORS in the Retina

    Retinitis pigmentosa (RP, MIM#268000) is a heterogeneous disease characterised by loss of rod photoreceptors and pigment deposits in the retina. Historically, genes linked to RP were associated with rod-specific functions. Recently, a novel class of

    http://iris.ucl.ac.uk/iris/publication/1033641/1

  5. Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins...

    USP14 is a cysteine protease deubiquitinase associated with the proteasome and plays important catalytic and allosteric roles in proteasomal degradation. USP14 inhibition has been considered a therapeutic strategy for accelerating degradation of

    http://iris.ucl.ac.uk/iris/publication/1719706/1

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