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  1. Synovial Th17 cells in juvenile idiopathic arthritis (JIA) express the Th17 master...

    http://iris.ucl.ac.uk/iris/publication/110718/1

  2. IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into...

    IL-7 is essential for the development and homeostasis of T and B lymphocytes and is critical for neonatal lymph node organogenesis because Il7-/- mice lack normal lymph nodes. Whether IL-7 is a continued requirement for normal lymph node structure

    http://iris.ucl.ac.uk/iris/publication/1540581/1

  3. c-Maf controls immune responses by regulating disease-specific gene networks and...

    The transcription factor c-Maf induces the anti-inflammatory cytokine IL-10 in CD4+ T cells in vitro. However, the global effects of c-Maf on diverse immune responses in vivo are unknown. Here we found that c-Maf regulated IL-10 production in CD4+ T

    http://iris.ucl.ac.uk/iris/publication/1549744/1

  4. The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell...

    BACKGROUND: Dynamic epigenetic alterations accompanying CD4+ T helper cell differentiation have been implicated in multiple autoimmune diseases. The bromodomain and extra-terminal (BET) proteins are epigenetic regulators that recognize and bind to

    http://iris.ucl.ac.uk/iris/publication/1624333/1

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