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  1. Collaborative Cross Mice Yield Genetic Modifiers for Pseudomonas aeruginosa Infection in...

    Human genetics influence a range of pathological and clinical phenotypes in respiratory infections; however, the contributions of disease modifiers remain underappreciated. We exploited the Collaborative Cross (CC) mouse genetic-reference population

  2. The human liver microenvironment shapes the homing and function of CD4+T-cell populations


    Background & Aims

    Tissue-resident memory T cells (T RM ) are important immune sentinels that provide efficient in situ immunity. Liver-resident CD8 + T RM have been previously described, and contribute to viral control in

  3. Genome-wide association study of bipolar disorder in Canadian and UK populations...

    BACKGROUND: Recently, genome-wide association studies (GWAS) for cases versus controls using single nucleotide polymorphism microarray data have shown promising findings for complex neuropsychiatric disorders, including bipolar disorder (BD). METHODS

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