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  1. TGFbeta protects mesoangioblasts from apoptosis via sphingosine kinase-1 regulation.

    Mesoangioblasts are vessel-derived progenitor cells that can be induced to differentiate into different cell types of the mesoderm such as muscle and bone. Here we examined the role of transforming growth factor-beta (TGFbeta), a pleiotropic

  2. A five-gene hedgehog signature developed as a patient preselection tool for hedgehog...

    PURPOSE: Distinct molecular subgroups of medulloblastoma, including hedgehog (Hh) pathway-activated disease, have been reported. We identified and clinically validated a five-gene Hh signature assay that can be used to preselect patients with Hh

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