Advanced search
Search:  

1 - 10 of 11 results found for TSG101. Did you mean: cs101

  1. Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward...

    http://iris.ucl.ac.uk/iris/publication/105100/1

  2. WASH and Tsg101/ALIX-dependent diversion of stress-internalised EGFR from the canonical...

    Stress exposure triggers ligand-independent EGF receptor (EGFR) endocytosis, but its post-endocytic fate and role in regulating signalling are unclear. We show that the p38 MAP kinase-dependent, EGFR tyrosine kinase (TK)-independent EGFR

    http://iris.ucl.ac.uk/iris/publication/1034440/1

  3. Identification of domains in Gag important for prototypic foamy virus egress

    Sequence motifs (L domains) have been described in viral structural proteins. Mutations in these lead to a defect at a late stage in virus assembly and budding. For several viruses, recruitment of an endosomal sorting complexes required for

    http://iris.ucl.ac.uk/iris/publication/1297034/7

  4. Analysis of HIV-1 Assembly on Intracellular Plasma Membrane-connected Compartments of...

    In primary human monocyte-derived macrophages (MDM), HIV assembles on complex intracellular plasma membrane-connected compartments (IPMCs). Currently, it is unclear whether, in addition to assembly at IPMCs, HIV uses the cell surface of MDM, as

    http://iris.ucl.ac.uk/iris/publication/998931/1

  5. ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and...

    Intracellular beta amyloid (Aβ) accumulation is a key feature of early Alzheimer’s disease (AD) and precedes the appearance of Aβ in extracellular plaques. Aβ is generated through proteolytic processing of amyloid precursor protein (APP), but

    http://iris.ucl.ac.uk/iris/publication/1034441/1

  6. Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification...

    RATIONALE: We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs),

    http://iris.ucl.ac.uk/iris/publication/868031/2

  7. Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking...

    Antibody combinations targeting cell surface receptors are a new modality of cancer therapy. The trafficking and signalling mechanisms regulated by such therapeutics are not fully understood but could underlie differential tumour responses. We

    http://iris.ucl.ac.uk/iris/publication/1744811/1

  8. Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune...

    Nanoparticle tracking analysis permits the determination of both the size distribution and relative concentration of microvesicles, including exosomes, in the supernatants of cultured cells and biological fluids. We have studied the release of

    http://iris.ucl.ac.uk/iris/publication/848996/2

  9. Mass spectrometry analysis reveals differences in the host cell protein species found in...

    © 2017. Lentiviral vectors (LVs) have been successfully used in clinical trials showing long term therapeutic benefits. Studying the role of cellular proteins in lentivirus HIV-1 life cycle can help understand virus assembly and budding, leading to

    http://iris.ucl.ac.uk/iris/publication/1528084/1

  10. Comparative analysis of cellular proteins in stably and transiently produced lentiviral...

    Lentiviral vectors (LVs) are successfully used in clinical trials showing long term therapeutic benefits. Studying the role of cellular proteins during replication of lentivirus HIV-1 helped to understand virus assembly and budding. Knowing what

    http://iris.ucl.ac.uk/iris/publication/969526/1

  11. Page: 1 2