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  1. Functional subsets of human helper-inducer cells defined by a new monoclonal antibody,...

    The monoclonal antibody UCHL1 identified an antigen present on most thymocytes, a subpopulation of resting T cells within both the CD4 and CD8 subsets, and on mature activated T cells. The UCHL1 determinant is also present on cells of the myeloid

    http://iris.ucl.ac.uk/iris/publication/154078/2

  2. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells

    A group of mAb recognizing the 200- and/or 220-kDa determinants (CD45R) of the leukocyte common Ag such as 2H4, WR16, MD4.3, and SN130 cross-block each other showing that they recognize a closely related epitope. The antibody UCHL1 reacts with a

    http://iris.ucl.ac.uk/iris/publication/256008/1

  3. Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's...

    Alzheimer's disease (AD) is characterized by protein aggregates, i.e. senile plaques and neurofibrillary tangles. The ubiquitin-proteasome system has been proposed a role in proteolytic removal of these protein aggregates. Ubiquitin carboxy-terminal

    http://iris.ucl.ac.uk/iris/publication/858544/2

  4. Proteomic Analysis After Status Epilepticus Identifies UCHL1 as Protective Against...

    © 2017, Springer Science+Business Media New York. Brief, non-harmful seizures (preconditioning) can temporarily protect the brain against prolonged, otherwise injurious seizures. Following focal-onset status epilepticus (SE) in preconditioned

    http://iris.ucl.ac.uk/iris/publication/1777453/1

  5. Cellular events during memory T-cell activation in vitro: the UCHL1 (180,000 MW)...

    After T-cell activation, a switch of leucocyte common antigen (LCA) expression occurs which is detected by the disappearance of CD45R and the appearance of UCHL1 positivity. Upon activation of CD45R+ T cells by phytohaemagglutinin (PHA), the IL-2

    http://iris.ucl.ac.uk/iris/publication/256216/2

  6. Ubiquitin carboxyl-terminal esterase L1 (UCHL1) S18Y polymorphism in patients with...

    BACKGROUND:  Cataract is characterized by light-scattering protein aggregates. The ubiquitin-proteasome system has been proposed a role in proteolytic removal of these protein aggregates. Ubiquitin carboxyl-terminal esterase L1 (UCHL1) is a

    http://iris.ucl.ac.uk/iris/publication/858499/2

  7. eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a...

    Understanding mechanisms that lead to selective motor neuron degeneration requires visualization and cellular identification of vulnerable neurons. Here we report generation and characterization of UCHL1-eGFP and hSOD1(G93A)-UeGFP mice, novel

    http://iris.ucl.ac.uk/iris/publication/1041010/2

  8. Antibodies | UCL Queen Square Institute of Neurology - UCL –...

    Fe, Bv, Ca, Gt, Sh, Pig. UCHL1 (CD45 Ro). ... DAKO. UCHL1. x.  .  .  . Ubiquitin. VBS. Polyclonal. x.  .  .  . Vimentin . DAKO. V9. x.  . x. Bv, Ha, Ca, Hs, Mk, Rb.

    https://www.ucl.ac.uk/ion/clinical-divisions/neuropathology/ucl-iqpath/histology/antibodies

  9. Immunohistological studies of surface antigen on colonic lymphoid cells in normal and...

    Mucosal samples from 16 patients with idiopathic inflammatory bowel disease were examined immunohistologically using several monoclonal antibody combinations, and the results were compared with those obtained in other colonic inflammatory disorders

    http://iris.ucl.ac.uk/iris/publication/157239/2

  10. Phenotypic analysis of malignant lymphoma in simian immunodeficiency virus infection...

    Primates infected with simian immunodeficiency virus (SIV) develop a condition similar to the human acquired immunodeficiency syndrome (AIDS). The close resemblance between the simian acquired immunodeficiency syndrome (SAIDS) and the human disease

    http://iris.ucl.ac.uk/iris/publication/779157/7

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