Related to YAP1
Advanced search

1 - 10 of 15 results found for YAP1. Did you mean: yap

  1. Novel heterozygous mutation in YAP1 in a family with isolated ocular colobomas

  2. Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and...

  3. New variant and expression studies provide further insight into the genotype-phenotype...

  4. NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium

  5. YAP1 drives ependymoma-like tumour formation in mice and post mitotic functions of LATS2...

    In a subset of paediatric ependymomas YAP1 (Yes-associated protein 1) gene fusions have been identified recently. In this study we show that YAP1 is expressed in the ventricular zone of the developing mouse brain. Depletion of two negative

  6. Heterozygous Loss-of-Function Mutations in YAP1 Cause Both Isolated and Syndromic Optic...

  7. NDR functions as a physiological YAP1 kinase in the intestinal epithelium

    Background Phosphorylation of the transcriptional coactivator YAP1 is a key event in defining Hippo signaling outputs. Previous studies demonstrated that phosphorylation of YAP1 at serine 127 (S127) sequesters YAP1 in the cytoplasm and consequently

  8. Investigation of YAP1 localisation and dynamics in tumour cell biology

    The complexity of the cancer is created by the fine interplay between cancer cells and their microenvironment. Cancer cells interact with various stromal cell types and extracellular matrix components during tumour growth and development of

  9. The Regulation and Function of YAP1

    Yes-associated protein 1 (YAP1) is a transcriptional regulator that was first described as part of the Hippo signalling cascade. In the last five years, several others regulators have been identified, placing YAP1 at the centre of a much more

  10. Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic...

    Exome sequence analysis of affected individuals from two families with autosomal-dominant inheritance of coloboma identified two different cosegregating heterozygous nonsense mutations (c.370C>T [p.Arg124*] and c. 1066G>T [p.Glu356*]) in YAP1. The

  11. Page: 1 2