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31 - 40 of 62 results found for CETP.

  1. Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase...

    Background: CETP inhibition reduces vascular event rates but confusion surrounds its low-density lipoprotein (LDL)-cholesterol effects. We sought to clarify associations of genetic inhibition of CETP on detailed lipoproteins. Methods and Results: We

    http://iris.ucl.ac.uk/iris/publication/1570534/1

  2. Cholesteryl Ester Transfer Protein as a Drug Target for Cardiovascular Disease

    Drug development of cholesteryl ester transfer protein (CETP) inhibition to prevent coronary heart disease (CHD) has yet to deliver licensed medicines. To distinguish compound from drug target failure, we compared evidence from clinical trials and

    http://iris.ucl.ac.uk/iris/publication/1816348/18

  3. Cholesteryl Ester Transfer Protein as a Drug Target for Cardiovascular Disease

    Drug development of cholesteryl ester transfer protein (CETP) inhibition to prevent coronary heart disease (CHD) has yet to deliver licensed medicines. To distinguish compound from drug target failure, we compared evidence from clinical trials and

    http://iris.ucl.ac.uk/iris/publication/1818974/18

  4. Interaction between dietary fat intake and the cholesterol ester transfer protein TaqIB...

    BACKGROUND: A low plasma HDL-cholesterol concentration is a major characteristic of diabetic dyslipidemia. HDL concentrations are determined by both environmental factors and genetic factors. Cholesterol ester transfer protein (CETP) plays an

    http://iris.ucl.ac.uk/iris/publication/915465/2

  5. Genotypic associations of the hepatic secretion of VLDL apolipoprotein B-100 in obesity

    We examined the effect of genetic polymorphisms of proteins regulating intrahepatic processing of apolipoprotein B-100 (apoB) and the supply of neutral lipids to the liver on the hepatic secretion of very low density lipoprotein (VLDL) apoB in

    http://iris.ucl.ac.uk/iris/publication/15512/1

  6. Cholesteryl ester transfer protein polymorphisms, statin use, and their impact on...

    The association of nonfunctional variants of the cholesteryl ester transfer protein (CETP) with efficacy of statins has been a subject of debate. We evaluated whether three functional CETP variants influence statin efficacy. The effect of CETP

    http://iris.ucl.ac.uk/iris/publication/915428/2

  7. Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase...

    Cholesteryl ester transfer protein (CETP) inhibition reduces vascular event risk, but confusion surrounds its effects on low-density lipoprotein (LDL) cholesterol. Here, we clarify associations of genetic inhibition of CETP on detailed lipoprotein

    http://iris.ucl.ac.uk/iris/publication/1732738/1

  8. Publications | UCL Institute of Health Informatics - UCL – University...

    Publications. IHI researchers publish extensively across wide range of academic journal. Below you will find details of their papers. Please click  here for a list of IHI publications spanning 2008-2017. 2021. Wood A et al. (2021). Linked

    https://www.ucl.ac.uk/health-informatics/research/publications

  9. Age-related effects of genetic variation on lipid levels: The Columbia University...

    OBJECTIVES: To examine the genotype:phenotype association in children compared with their parents. METHODS: Variations at 4 key gene loci, namely lipoprotein lipase (LPL S447X), hepatic lipase (HL -480C>T), cholesteryl ester transfer protein (CETP

    http://iris.ucl.ac.uk/iris/publication/21246/1

  10. Variants in the cholesterol ester transfer protein and lipoprotein lipase genes are...

    There are no definitive explanations as to why individuals with hypercholesterolemia, a major cardiovascular risk factor, respond differently to dietary change. Fifty five free-living individuals completed a double crossover trial with two dietary

    http://iris.ucl.ac.uk/iris/publication/15439/1

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