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1 - 10 of 96 results found for nrp1.

  1. Research | UCL Institute of Ophthalmology - UCL – University College...

    Macrophages help blood vessel sprouts to fuse into perfused circuits. Dual NRP1 role in VEGF and matrix signalling for retina angiogenesis. ... VEGF signals through NRP1 for proper neuronal migration and survival. VEGF signals through NRP1 to guide axons

    https://www.ucl.ac.uk/ioo/research/ruhrberg-lab/research

  2. VEGF (Vascular Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs...

    http://iris.ucl.ac.uk/iris/publication/1561350/1

  3. Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel...

    http://iris.ucl.ac.uk/iris/publication/922537/3

  4. VEGF(189) binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the...

    http://iris.ucl.ac.uk/iris/publication/1000830/3

  5. ruhrberg | UCL Institute of Ophthalmology - UCL – University College...

    To understand NRP1 function, we are identifying roles for these NRP1 ligands in both blood vessels and nerves. ... Moreover, we have found that SEMA3A/NRP1 signalling patterns the peripheral nervous system by enabling neural crest cell guidance.

    https://www.ucl.ac.uk/ioo/research/academics/ruhrberg

  6. VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the...

    The vascular endothelial growth factor (VEGFA, VEGF) regulates neurovascular patterning. Alternative splicing of the Vegfa gene gives rise to three major isoforms termed VEGF121, VEGF165 and VEGF189. VEGF165 binds the transmembrane protein

    http://iris.ucl.ac.uk/iris/publication/1000830/2

  7. Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel...

    Neuropilin 1 (NRP1) is a receptor for class 3 semaphorins and vascular endothelial growth factor (VEGF) A and is essential for cardiovascular development. Biochemical evidence supports a model for NRP1 function in which VEGF binding induces complex

    http://iris.ucl.ac.uk/iris/publication/922537/2

  8. Key Publications | Centre for Cardiometabolic and Vascular Science -...

    2018).  VEGF (Vascular Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs (a Disintegrin and Metalloproteinase) 9 and 10 to Generate Novel Carboxy-Terminal NRP1 Fragments That Regulate Angiogenic Signaling.

    https://www.ucl.ac.uk/cardiometabolic-vascular-science/publications/key-publications

  9. VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration,...

    In endothelial cells, neuropilin-1 (NRP1) binds vascular endothelial growth factor (VEGF)-A and is thought to act as a coreceptor for kinase insert domain-containing receptor (KDR) by associating with KDR and enhancing VEGF signaling. Here we report

    http://iris.ucl.ac.uk/iris/publication/347215/1

  10. VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration,...

    In endothelial cells, neuropilin-1 (NRP1) binds vascular endothelial growth factor (VEGF)-A and is thought to act as a coreceptor for kinase insert domain-containing receptor (KDR) by associating with KDR and enhancing VEGF signaling. Here we report

    http://iris.ucl.ac.uk/iris/publication/347215/2

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