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1 - 10 of 67 results found for pik3ca.

  1. Cancer drug could treat blood vessel deformities | UCL News - UCL –...

    Our colleagues at MSK then tested drugs on the mice that directly inhibit PIK3CA, developed to treat cancer. ... Although PIK3CA inhibitors are more specific than many cancer drugs, they still could have unpleasant side effects inside the body.

    https://www.ucl.ac.uk/news/2016/mar/cancer-drug-could-treat-blood-vessel-deformities

  2. Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

    © 2018 The Authors PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found in benign overgrowth syndromes, collectively known as PIK3CA-related overgrowth spectrum (PROS). As in cancer, PIK3CA mutations in

    http://iris.ucl.ac.uk/iris/publication/1586796/1

  3. Activation of the MACC1/PIM/cMyc axis confers resistance to PI3K/mTOR inhibition in...

    http://iris.ucl.ac.uk/iris/publication/1835221/3

  4. Absence of predictive deep phenotyping variables in PIK3CA mosaicism

    http://iris.ucl.ac.uk/iris/publication/1209763/3

  5. Deep phenotyping and next generation sequencing for PIK3CA-related overgrowth spectrum

    http://iris.ucl.ac.uk/iris/publication/1182068/3

  6. Evaluation of PIK3CA mutation as a predictor of benefit from NSAID therapy in colorectal...

    http://iris.ucl.ac.uk/iris/publication/919099/11

  7. Are the Benefits of Aspirin in Colorectal Cancer Limited to PIK3CA Mutated Cancers?

    http://iris.ucl.ac.uk/iris/publication/1774218/7

  8. FOCUS4-D: Results from a randomised, placebo controlled trial (RCT) of AZD8931 (an...

    http://iris.ucl.ac.uk/iris/publication/1212929/1

  9. Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal...

    http://iris.ucl.ac.uk/iris/publication/906709/3

  10. Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner

    The PIK3CA gene, which encodes the p110α catalytic subunit of PI3 kinase (PI3K), is mutationally activated in cancer and in overgrowth disorders known as PIK3CA-related overgrowth spectrum (PROS). To determine the consequences of genetic PIK3CA

    http://iris.ucl.ac.uk/iris/publication/1645152/1

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